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A • Part B • Part
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Journal
Aims and Scope - Part B
Developmental and Reproductive
Toxicology
The purpose of this journal
is to publish original contributions describing the toxicity of
chemicals to developing organisms and the process of reproduction.
The scope of the journal will include:
- toxicity of new chemical entities and biotechnology
derived products to developing organismal systems;
- toxicity of these and other xenobiotic agents
to reproductive function;
- multi-generation studies;
- endocrine-mediated toxicity, particularly for
endpoints that are relevant to development and reproduction;
- novel protocols for evaluating developmental
and reproductive toxicity;
- approaches to the application of risk assessment
for developmental and reproductive toxicants;
- toxicity related to direct exposure in juvenile
animals.
Studies with in vivo and in vitro
model systems will be the primary focus of the journal. Studies
conducted to comply with regulations for the registration of pharmaceuticals,
agro chemicals, chemicals or biotechnology derived products and
provide data for safety/risk assessments are welcome, including
testing to fulfill requirements for high-production volume, assessment
of children’s health, endocrine disruptor screening and testing,
and other governmentally mandated programs. Inclusion of comprehensive
data that are necessary for complete interpretation of study results
is encouraged, and tables and figures that are too extensive to
publish in hard copy may be made available through an associated
website.
Manuscripts will be judged based on the appropriateness
of the experiments, quality of the data, the presence of multiple
dose levels, adequate statistical power, and the presence of information
that allows estimation of the potential risk to human reproduction
or development. The outcome of a study (i.e., whether an agent
is a reproductive hazard) will not be used as criterion for acceptance
of a manuscript.
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