Login | Contact Us | Join | Site Map | TS Home
Annual Meeting 2013
Meeting Information Program Registration Hotel Abstracts Students & Postdoc Sponsors
Meeting Program

(information subject to change)

Overview | Friday | Saturday | Sunday | Monday | Tuesday | Wednesday | Thursday

Tuesday, June 25, 2013

 

 

6:30 AM–7:00 AM SUNRISE MINI COURSE: COFFEE AND CONTINENTAL BREAKFAST—Salon B
   
7:00 AM–8:00 AM DINE WITH A TERATOLOGY AMBASSADOR
  (Advance Signup Required)
   

7:00 AM–5:00 PM

REGISTRATION—Grand Ballroom Foyer

 

 

7:00 AM–5:00 PM

SPEAKER READY ROOM OPEN

   

7:00 AM–8:30 AM

SUNRISE MINI COURSE (Separate Registration Required)—Salon B

  Advanced Technologies in Genetics and Genomics: Applications to the Prevention of Birth Defects and the Communication of Risk
  Organized by the Education Committee, Chairperson, Ali S. Faqi, MPI Research
   
7:00 AM–7:45 AM Current Technologies in Genetic Testing
  Maximilian Muenke, National Human Genome Research Institute, NIH
   
7:45 AM–8:30 AM Applications of Technologies and Communication of Risk
  Elaine M. Faustman, University of Washington
   
8:30 AM–9:15 AM SPECIAL LECTURE—Salon B
  Clinical and Molecular Teratology
  Chairperson: Elaine Z. Francis, Sandcastle Toxicology Associates
  Lecturer: Michel Vekemans, Université Paris Descartes
   

9:15 AM–12:25 PM

WILEY-BLACKWELL SYMPOSIUM—Salon B

 

Application of Imaging Technologies in Birth Defects Research and Clinical Practice

  Chairpersons: Ali S. Faqi, MPI Research and Susan Makris, US Environmental Protection Agency

 

Endorsed by the Publications Committee

9:15 AM–9:50 AM S23 Visualizing Complex Cell Dynamics in the Living Embryo
    Paul M. Kulesa, Stowers Institute for Medical Research
     
9:50 AM–10:25 AM S24 Imaging Modalities for High-Throughput Phenotyping of Structural Birth Defects in Mutagenized Fetal and Newborn Mice
    Kimimasa Tobita, Children’s Hospital of University of Pittsburgh Medical School
     
10:25 AM–10:40 AM   Break
     
10:40 AM–11:15 AM S25 Ultrasound Imaging in Research and Clinical Medicine
    Michael A. Schellpfeffer, Medical College of Wisconsin
     
11:15 AM–11:50 AM S26 Advances in Micro-CT Imaging for Preclinical Developmental Toxicology Evaluation
    L. David Wise, Merck Research Labs
     
11:50 AM–12:25 PM S27 Brain Imaging Studies on Early Brain Development in Children with Prenatal Nicotine Exposure
    Linda Chang, John A. Burns School of Medicine, University of Hawaii

 

 

12:25 PM–1:30 PM LUNCH ON YOUR OWN
   
12:30 PM–1:30 PM PUBLIC AFFAIRS COMMITTEE MEETING—Executive Boardroom
   
12:30 PM–1:30 PM PUBLICATIONS COMMITTEE MEETING—Santa Rita
   
1:30 PM – 2:45 PM TS/ETS EXCHANGE LECTURE—Salon B
  Myth of Merit: The Use of a Second Species in Developmental Toxicity Testing
 

Chairperson: Graham P. Bailey, Janssen Pharmaceutical N.V.

 

European Teratology Society

  More Safe Drugs by Less In Vivo Testing? (L4)
  Georg Schmitt, Hoffmann-LaRoche, Ltd.
   
  Teratology Society
  Screening Environmental Agents (L5)
 

Susan L. Makris, US Environmental Protection Agency

 

 

2:45 PM–5:15 PM PLATFORM SESSION 4—Catalina Ballroom
  In Vitro, Computational, and Alternative Methods and Models for Screening Developmental Toxicants
 

Chairpersons: Susan Euling, US Environmental Protection Agency and Michael F. O'Hara, Covance Laboratories, Inc.

2:45 PM–3:00 PM   Introduction
     
3:00 PM–3:15 PM 25 Identification of Pathways of Developmental Neurotoxicity by Metabolomics in a 3-D Organotypic Brain Cell Model Exposed to Lead Chloride
   

Hogberg HT1, Bouhifd M1, Dao T1, Harris G1, Kleensang A1, Nolan SJ1, Odwin-DaCosta S1, Pamies D1, Smirnova L1, van Vliet E2, Welles H1, Zhao L1, Hartung T1. 1The Johns Hopkins University, Bloomberg School of Public Health, Center for Alternative to Animal Testing, Baltimore, MD, United States, 2University of Barcelona, Fetal and Perinatal Medicine Research Group, August Pi i Sunyer Biomedical Research Institute, Hospital Clinic, Barcelona, Spain.

     
3:15 PM–3:30 PM 26 Computational Embryology and Predictive Toxicology of Cleft Palate
   

Sipes NS1, Hutson MS2, Baker NC1, Knudsen TB1. 1US EPA/ORD/NCCT, Research Triangle Park, NC, United States, 2Departments of Physics & Astronomy and Biological Sciences, Vanderbilt University, Nashville, TN, United States.

     
3:30 AM–3:45 PM 27 Effects of Perfluorinated Chemicals on Adipocyte Development
    Watkins AM, Wood CR, Lin MT, Abbott BD. US EPA, Research Triangle Park, NC, United States.
     
3:45 PM–4:00 PM   Break
     
4:00 PM–4:15 PM 28 The Use of Genetic Model Systems for Assessing Environmental Effects on Reproduction
    Kleinstreuer N1, Knudsen T1, Colaiacovo M2, Allard P3. 1NCCT, US EPA, Research Triangle Park, NC, United States, 2Harvard Medical School, Boston, MA, United States, 3UCLA, Los Angeles, CA, United States.
     
4:15 PM–4:30 PM 29 Effects of Bulk- and Nano-Vitamin A in Postimplantation Rat Embryos Cultured In Vitro
   

Di Renzo F, Bacchetta R, Menegola E. Università degli Studi di Milano, Milano, Italy.

     
4:30 AM–4:45 PM 30 Teratogenic Effects of Mixtures of Azole Fungicides Assessed by Using a New Dysmorphogenic Method for Branchial Arch Defects Evaluation
    Menegola E, Di Renzo F. Università degli Studi di Milano, Milan, Italy.
     
4:45 PM–5:00 PM 32 Interactive Effects of Methylmercury and Other Stressors: Daphnia pulex As an Alternative Model Organism for Early-Life Exposures
    Gohlke JM, Doke D. University of Alabama at Birmingham, Birmingham, AL, United States.
     
5:00 PM–5:15 PM   Discussion
   

2:45 PM–5:30 PM

TS/OTIS JOINT SYMPOSIUM
Cancer and Pregnancy: Considerations regarding the Use of Chemotherapy—Salon B

 

Chairpersons: Kembra Howdeshell and Michael Shelby, National Toxicology Program, NIEHS

 

 

2:45 PM–2:50 PM   Introduction
    Kembra Howdeshell, National Toxicology Program, NIEHS
     
2:50 PM–3:20 PM S28 Prenatal Care for the Pregnant Cancer Patient
    Elyce H. Cardonick, Cooper Health System
     
3:20 PM–3:50 PM S29 Detection and Administration of Systemic Therapies for Breast Cancer during Pregnancy
    Jennifer K. Litton, University of Texas MD Anderson Cancer Center
     
3:50 PM–4:05 PM   Break
     
4:05 PM–4:35 PM S30 Summary of National Toxicology Program Monograph on Developmental Effects of Cancer Chemotherapy Administered during Pregnancy
    Kembra Howdeshell, National Toxicology Program, NIEHS
     
4:35 PM–5:05 PM S31 Oncofertility: Expanding the Parenthood Options for Life after Cancer
    Laxmi A. Kondapalli, University of Colorado, Anschutz Medical Campus
     
5:05 PM–5:30 PM   Discussion
   
5:30 PM–7:30 PM TS/OTIS JOINT POSTER SESSION 2 AND EXHIBITS OPEN—Kiva Ballroom

Click Here to Browse Posters

P19

Pouliot L1, Robinson K1, Freke M1, Lewis E3, Perras R2, Hoberman A3. 1Charles River PCS-MTL, Senneville, QC, Canada, 2Charles River Canada, St-Constant, QC, Canada, 3Charles River PCS-PA, Horsham, PA, United States. Diet Acclimation of New Zealand White (NZW) Rabbits for Use in Embryo-Fetal Development Studies

 

P20

Coder PS, Tanchevski E, Mesnard JL, Sloter ED, Stump DG. WIL Research, Ashland, OH, United States. A Comparative Assessment of Four In Vivo Assays Included in the Tier 1 Screening Battery for the Endocrine Disruptor Screening Program (EDSP) in the Sprague Dawley Rat

 

P21

Parker RM, Baxter GE, Croft L. Huntingdon Life Sciences, East Millstone, NJ, United States. Control Data from the Four Combined Male/Female Rat Pubertal Assays (OPPTS 870.1500 & 870.1450) Plus Two Validation Studies

 

P22

Hui JY1, Foy JW-D1, Schroeder R2. 1Celgene Corporation, Summit, NJ, United States, 2MPI Research, Inc., Mattawan, MI, United States. Effects of Pomalidomide on the Fertility and Embryo-Fetal Development in Rats

 

P23

Garg M, Kharat A, Gutierrez H, Wohlert E, Stephens E, Savage D, Leeman L, Bakhireva L. University of New Mexico Health Sciences Center, Albuquerque, NM, United States. The Effect of Concomitant Drug Use on Adverse Perinatal Outcomes in Opioid-Maintenance Patients

 

P24

FADEL RA1, AL-FARK MM2, SALEM A-H1, SQUEIRA RP3, ABU-HIJLEH MF1. 1Department of Anatomy, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain, 2Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia, 3Department of Pharmacology & Therapeutics, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain. Effects of Prenatal Administration of Therapeutic Doses of Topiramate on Ossification of Craniofacial Bones in Rat Fetuses

 

P25

Di Bona KR, Vincent CE, Hayles H, Ramirez P, Pledger LA, Fair D, Rasco JF. The University of Alabama, Tuscaloosa, AL, United States. Functionalization of Nanoparticles for Drug Delivery May Influence Reproductive Toxicity in CD-1 Mice

 

P26

Henderson BW, Ajjuri RR., Boyd S, Daigle G, Bao Y, O'Donnell JM. The University of Alabama, Tuscaloosa, AL, United States. Low Doses of Iron-Oxide Nanoparticles Have a Detrimental Effect on Reproduction and Development

 

P27

Potineni H1, Ferguson E1, Melin VE1, Hrubec TC1,2. 1VA-MD Regional College of Veterinary Medicine, VA Tech, Blacksburg, VA, United States, 2E. Via College of Osteopathic Medicine, Virginia Campus, Blacksburg, VA, United States. Carbamazepine in Surface Water is Not Associated with NTDs in Mice

 

P28

Melin VE1, Geyer CB2, Hrubec TC1,3. 1Virginia Tech, Biomedical Sciences and Pathobiology, Blacksburg, VA, United States, 2Brody School of Medicine Department of Anatomy and Cell Biology, East Carolina University, Greenville, NC, United States, 3E. Via College of Osteopathic Medicine Virginia Campus, Blacksburg, VA, United States. Mouse Epididymal Sperm Counts following Exposure to Quaternary Ammonium Disinfectants

 

 

P29

Miller BM1, Kim H1, Herring BJ1, Kim DK1, Wells KK1, Axman JE1, Brady JA1, Lam X1, Crowe AR1, Jiang L1, Hood RD2,3, Bailey MM1. 1Emporia State University, Emporia, KS, United States, 2The University of Alabama, Tuscaloosa, AL, United States, 3Ronald D. Hood & Associates, Tuscaloosa, AL, United States. Exposure to Luteolin Exacerbates Cyclophosphamide Teratogenesis in CD-1 Mice

 

P30

Bailey GP1, Coogan T P2, Krayer JH2. 1Janssen R&D, Beerse, Belgium, 2Janssen R&D, Spring House, United States. The Mouse May Not Be an Appropriate Species for Evaluation of Reproductive and Developmental Toxicity for Human Monoclonal Antibodies

 

P31

El Husseini NK, Hales BF. McGill University, Montreal, QC, Canada. Does Nitrosative Stress Play a Role in Mediating the Embryotoxicity Induced by Hydroxyurea?

 

P32

Lamparter C, Cutler G, Winn L. Queen's University, Kingston, ON, Canada. Recombinational Repair of DNA Strand Breaks in Valproic Acid-Induced Teratogenesis

 

P33

Philbrook NA, Winn LW. Queen's University, Kingston, ON, Canada. Induction of NADPH Dehydrogenase Quinone 1 (NQO1) by Sulforaphane in Nonpregnant and Pregnant CD-1 Mice

 

P34

Chen X1, Nolen G1, Hansen DK1, Fisher E2, Harrouk W2, Tassinari MS2, Inselman AL2. 1US FDA/NCTR, Jefferson, AR, United States, 2US FDA/CDER, Silver Spring, MD, United States. Developing Osteoblasts As an Endpoint for the Mouse Embryonic Stem Cell Test in Prediction Toxicology

 

P35

Nichols H, Jeffay S, Hoopes M, Rosen M, Chandler K, Hunter S. ISTD, NHEERL, US EPA, Research Triangle Park, NC, United States. Evaluation of Stage-Dependent Sensitity to Chemical-Induced Perturbation in Mouse Embryonic Stem Cells

 

P36

Jeffay S, Hoopes M, Nichols H, Rosen M, Chandler K, Hunter S. ISTD, NHEERL, US EPA, Research Triangle Park, NC, United States. Evaluation of Chemical-Induced Effects Using a Gastrulation Endpoint in Mouse Embryonic Stem Cell ACDC Assay

 

P37

Stokes SE, Winn LM. Queen's University, Kingston, ON, Canada. Examining the Role of NF-κB and P38-MAPK in Benzoquinone-Induced Changes in C-MYB Activity in HD3 Cells

 

P38

McNerney ME1, Augustine K2, Breslin W3, Bushdid P4, Chapin R5, Enright B6, Green M7, Hew KK8, Hui J9, Kenjie A10, McGinnis C11, Moffat G12, Moffit J13, Stewart J14, Thullen T15, Van den Bulck K16. 1Bristol-Myers Squibb, New Brunswick, NJ, United States, 2Bristol-Myers Squibb, Hopewell, NJ, United States, 3Eli Lilly, Indianapolis, IN, United States, 4GlaxoSmithKline, Upper Merion, PA, United States, 5Pfizer, Groton, CT, United States, 6AbbVie, Chicago, IL, United States, 7Merck, West Point, PA, United States, 8Takeda, Chicago, IL, United States, 9Celgene, Summit, NJ, United States, 10Genentech, San Francisco, CA, United States, 11Roche, Basel, Switzerland, 12Amgen, Thousand Oaks, CA, United States, 13Boehringer-Ingelheim, Ridgefield, CT, United States, 14AstraZeneca, Aldersley Park, United Kingdom, 15Vertex, Cambridge, MA, United States, 16Janssen, Beerse, Belgium. IQ Consortium for Innovation and Quality in Pharmaceutical Development Preclinical Safety Leadership Group Initiative: Predictivity of Three In Vitro Assays for Nonclinical In Vivo Developmental Toxicity

 

P39

Ellis-Hutchings RG, Boverhof D, Settivari R, Carney EW. The Dow Chemical Company, Midland, MI, United States. An Integrated Assay to Simultaneously Predict Mammalian Teratogenicity and Acute Fish Toxicity Using Zebrafish Embryos

 

P40

Nowland WS, Campion SN, Coburn A, Kumpf SW, Stethem CM, Koitz R, Stedman DB. Pfizer Worldwide Research and Development, Groton, CT, United States. Success of Zebrafish in Predicting Embryo Fetal Developmental Abnormalities in Mammals

 

P41

Stanko JP1, Kissling GE2, Fenton SE1. 1National Toxicology Program Laboratory, NIEHS, Research Triangle Park, NC, United States, 2Biostatistics Branch, NIEHS, Research Triangle Park, NC, United States. A Novel Quantitative Method for the Comparison of Mammary Gland Development in Multiple Strains of Rat

 

P42

Wolton K1, Wright J2, Hentges K1, Barnes E2. 1University of Manchester, Manchester, United Kingdom, 2Syngenta UK, Bracknell, United Kingdom. Exploring the Role of the Mediator Gene ‘Med31’ in Proliferation and Limb Development during Mouse Embryogenesis.

 

P43

Rengasamy P. Central Michigan University College of Medicine, Mt. Pleasant, MI, United States. Intrauterine Growth Restriction (IUGR) and Skeletal Defects in Fetuses of Diabetic Mice Treated with Fluconazole

 

P44

Infante S1,2, Oberhauser A2, Perez-Polo R2. 1Northern Kentucky University, Highland Heights, KY, United States, 2University of Texas Medical Branch, Galveston, TX, United States. Bax Phosphorylation Is Associated with Subcellular Localization and Oligomerization after Neonatal Hypoxia-Ischemia in Wistar Rats

   
   


Share this page.