TS 2010 Annual Meeting

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Meeting Program

(information subject to change)

Tuesday, June 29, 2010

6:30 AM–7:00 AM	Sunrise Mini Course Coffee and Continental Breakfast—Marriott Ballroom VI

7:00 AM–5:00 PM	Registration—Marriott Ballroom VI Foyer

7:00 AM–8:20 AM	Sunrise Mini Course (Separate registration required)—Marriott Ballroom VI
	Imaging Tools for Structural and Functional Teratogenesis Analyses
	Organized by the Education Committee, Chairperson, Louise M. Winn, Queen’s University

7:00 AM–7:40 AM	Imaging Tools for Structural Analysis
	William Slikker, Jr., National Center for Toxicological Research, U.S. FDA

7:40 AM–8:20 AM	Imaging Tools for Functional Analysis
	Julia M. Stephen, University of New Mexico

8:00 AM–2:00 PM	Exhibit Hall Open—Marriott Ballroom I

8:30 AM–9:15 AM	TS/NBTS/OTIS Joint Special Lecture—Marriott Ballroom VI
	Children's Environmental Health: A Good Start Lasts a Lifetime
	Linda S. Birnbaum, National Institute of Environmental Health Sciences

9:15 AM–9:30 AM	Break—Marriott Ballroom I

9:30 AM–12:00 NOON	March of Dimes/Public Affairs Committee Symposium—Marriott Ballroom VI
	Herbal Supplement Usage during Pregnancy
	Chairpersons: Patricia M. Bittner, U.S. Consumer Product Safety Commission, Chair, Public Affairs Committee and Richard K. Miller, University of Rochester Medical Center
	Organized by the Public Affairs Committee
9:30 AM–10:00 AM	Herbal Usage during Pregnancy: Teratology Society White Paper
	Richard K. Miller, University of Rochester Medical Center

10:00 AM–10:30 AM	Herbal Preparations Usage and Pregnancy
	Henry M. Hess, University of Rochester Medical Center

10:30 AM–11:00 AM	Herbal Products: Are They What They Claim to Be?
	William R. Obermeyer, ConsumerLab.com

11:00 AM–11:10 AM	Herbal Drugs in Pregnancy: A Canadian Perspective
	Gideon Koren, The Hospital for Sick Children

11:10 AM–11:20 AM	Traditional Chinese Medicine: Herbal Medicine Origins and Utilization in China
	Robert L. Brent, Alfred I. duPont Hospital for Children

11:20 AM–11:30 AM	Herbal Preparations: Are We at the Beginning of Regulations? The Situation in Europe and the Eastern Mediterranean Region
	Asher Ornoy, Hebrew University Hadassah Medical School and Israeli Ministry of Health

11:30 AM–12:00 NOON	Panel Discussion of Position Paper and Topic
	Patricia M. Bittner, U.S. Consumer Product Safety Commission, Chair, Public Affairs Committee

9:30 AM–12:00 NOON	Joint TS/NBTS Symposium—Marriott Ballroom VII
	Advancing Neurodevelopmental Evaluation in Children: An Interdisciplinary Approach
	Chairperson: Susan Makris, U.S. Environmental Protection Agency

9:30 AM–9:55 AM	The Use of Neurodevelopmental Data in Children for Risk Assessment of Environmental Chemicals
	Susan Makris, U.S. Environmental Protection Agency

9:55 AM–10:20 AM	A Multidisciplinary Approach to Advancing the Science of Neurodevelopmental Testing in Cohorts of Infants and Young Children
	Judy S. LaKind, LaKind Associates, LLC

10:20 AM–10:45 AM	Getting the Biggest Bang for Your Buck: Choosing Neurodevelopmental Tests That Maximize Power
	Lauren Kenworthy, George Washington University Medical School

10:45 AM–11:10 AM	Threats to Study Validity: The Flynn Effect, Examiner Drift, Confounders, Lost in Translation, and Other Important Considerations
	Laura Gutermuth Anthony, George Washington University School of Medicine

11:10 AM–11:35 AM	Weight-of-the-Evidence Assessment in Neurodevelopmental Epidemiology: A Plea for Consistency
	Michael Goodman, Emory University

11:35 AM–12:00 NOON	Panel Discussion

12:00 NOON–2:00 PM	TS/NBTS Joint Poster Session and Exhibits Open—Marriott Ballroom I
	Tuesday Poster Session Listings

2:00 PM–4:30 PM	Platform Session III—Marriott Ballroom VI
	Hazard Assessment and Screening

2:00 PM–2:15 PM	Effects of In Utero Exposure to Mono-2-ethylhexylphthalate (MEHP) on the Adult Female Mouse
	Moyer BJ, Hixon ML. Brown University, Providence, RI, United States.

2:15 PM–2:30 PM	Micro-CT and Alizarin Red Evaluations of Fetal Rat and Rabbit Skeletal Abnormalities Induced by All-Trans-Retinoic Acid
	Wise LD¹, Xue D², Winkelmann CT². ¹Toxicological Sciences, Merck Research Laboratories, West Point, PA, United States, ²Imaging Department, Merck Research Laboratories, West Point, PA, United States.

2:30 PM–2:45 PM	Effects of Bisphenol A and Diethylstilbestrol on the Adult Male Reproductive System Following Oral Administration to Pregnant C57BL6 Mice on Gestational Days 10 through 16
	Hixon ML, LaRocca J, Boyajian A, Brown C, Duncan Smith S. Brown University, Providence, RI, United States.

2:45 PM–3:00 PM	Gonadal Responses to Vinclozolin Administered Orally to Han Wistar Rats
	Tyl RW¹, Seely JC², Marr MC¹, Myers CB¹, Youn VY¹, Browning DB¹, Bishop JB³. ¹RTI International, Research Triangle Park, NC, United States, ²Experimental Pathology Laboratories, Inc., Research Triangle Park, NC, United States, ³National Toxicology Program/NIEHS/NIH, Research Triangle Park, NC, United States.

3:00 PM–3:15 PM	Break

3:15 PM–3:30 PM	Maternal Diet Modulates the Rate of Neural Tube Defects in Diabetic Pregnancies
	Kappen C, Kruger C, MacGowan J, Salbaum JM. Pennington Biomedical Research Center, Baton Rouge, LA, United States.

3:30 PM–3:45 PM	Mammary Gland Development As a Sensitive Indicator of Early Life Exposures: Recommendations from an Interdisciplinary Workshop
	Fenton SE¹, Rudel RA², Euling SY³, Makris SL³. ¹National Institute of Environmental Health Sciences, National Toxicology Program, Research Triangle Park, NC, United States, ²Silent Spring Institute, Newton, MA, United States, ³NCEA, U.S. EPA, Washington, DC, United States.

3:45 PM–4:00 PM	Assessment of Reproductive and Developmental Toxicity of Mixtures of Regulated Drinking Water Chlorination By-Products in a Multigenerational Rat Bioassay
	Narotsky MG¹, Klinefelter GR¹, Goldman JM¹, Strader LF¹, Suarez JD¹, Pressman JG², Miltner RJ², Speth T², Teuschler LK³, Rice GE³, Richardson SD⁴, Best DS¹, McDonald A¹, Murr AS¹, Hunter ES¹, Simmons JE¹. ¹National Health and Environmental Effects Research Laboratory, ORD, U.S. EPA, Research Triangle Park, NC, United States, ²National Risk Management Research Laboratory, ORD, U.S. EPA, Cincinnati, OH, United States, ³National Center for Environmental Assessment, ORD, U.S. EPA, Cincinnati, OH, United States, ⁴National Exposure Research Laboratory, ORD, U.S. EPA, Athens, GA, United States.

4:00 PM–4:15 PM	A Fishy Solution to Reproductive Toxicity Screening or Just a Red Herring? Zebrafish in Developmental Toxicity: Value within Pharmaceutical Development
	Van den Bulck K¹, Hill A², Jones M², Dodd A², Mesens N¹, Bailey GP¹, De Schaepdrijver L¹, Lammens L¹. ¹Johnson & Johnson Pharmaceutical Research & Development, Beerse, Belgium, ²Evotec AG, Hamburg, Germany.

4:15 PM–4:30 PM	Establishment of a Statistical Prediction Model and Abbreviated Assay Design for Teratogenicity Screening of Compounds Using Rat Whole Embryo Culture
	Zhang CXZ, Cao JC, Panzica-Kelly JPK, Stock DS, Augustine-Rauch KAA. Bristol Myers Squibb, Pennington, NJ, United States.


2:00 PM–4:15 PM	TS/OTIS Joint Platform Session IV —Marriott Ballroom IX
	Common Conditions in Pregnancy: Treatment of Mental Health and Asthma

2:00 PM–2:15 PM	Patterns of Psychotropic Drug Use in Pregnancy and Lactation: The MotherSafe Experience 2000–2007
	Eamus M1, Oei J^1,2, Hill M³, Taylor T³, Kennedy D^1,3. ¹School of Women’s and Children’s Health, University of NSW, Kensington, NSW, Australia, ²Dept. of Neonatology, Royal Hospital for Women, Randwick, NSW, Australia, ³MotherSafe, Royal Hospital for Women, Randwick, NSW, Australia.

2:15 PM–2:30 PM	Birth Defects, Preterm Bi rth and Intrauterine Growth in the Offspring of Women Prescribed Citalopram during Pregnancy
	Colvin L^1,2, Slack-Smith L², Stanley FJ¹, Bower C¹. ¹Centre for Child Health Research, Telethon Institute for Child Health Research, The University of Western Australia, West Perth, Australia, ²School of Dentistry, The University of Western Australia, West Perth, Australia.

2:30 PM–2:45 PM	The Safety of Escitalopram in Pregnancy: A Prospective Cohort Study
	Klieger-Grossmann C¹, Weitzner B¹, Einarson T², Koren G¹, Einarson ?A¹. ¹The Motherisk Program, Division of Clinical Pharmacology and Toxicology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, ²Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.

2:45 PM–3:00 PM	Neurodevelopment of Children Exposed In Utero to Venlafaxine: Preliminary Results
	Nulman I^1,2, Barrera M^1,2, Pulver A¹, Streiner D^2,3, Feldman B^1,2, Koren G^1,2. ¹The Hospital for Sick Children, Toronto, ON, Canada, ²The University of Toronto, Toronto, ON, Canada, ³Baycrest Centre, Toronto, ON, Canada.

3:00 PM–3:15 PM	Break

3:15 PM–3:30 PM	Impact of Changing the Dose of Inhaled Corticosteroids during Pregnancy on the Risk of Maternal Asthma Exacerbations
	Blais L^1,2, Kettani F², Ducharme FM³, Lemière C^1,2, Beauchesne M-F¹, Bérard A¹. 1Université de Montréal, Montréal, QC, Canada, ²Hôpital du Sacré-Coeur de Montréal, Montréal, QC, Canada, ³CHU Ste-Justine, Montréal, QC, Canada.

3:30 PM–3:45 PM	Congenital Anomalies in Asthmatic Women Using Corticosteroids during Pregnancy: A Meta Analysis from Published Data
	Namazy JA¹, Murphy VE^2,3, Powell H^2,4, Gibson PG^2,4, Chambers CD⁵, Schatz M⁶. ¹Scripps Clinic, San Diego, CA, United States, ²University of Newcastle, Newcastle, NSW, Australia, ³Hunter Medical Research Institute, Newcastle, NSW, Australia, ⁴John Hunter Hospital, Newcastle, NSW, Australia, ⁵University of California San Diego, La Jolla, CA, United States, ⁶Kaiser Permanente Medical Center, San Diego, CA, United States.

3:45 PM–4:00 PM	Risk of Perinatal Mortality Associated with the Use of Inhaled Corticosteroids for the Treatment of Asthma during Pregnancy
	Breton MCB¹, Beauchesne MFB^1,2, Lemière CL², Rey ER³, Amélie AF², Blais LB^1,2. ¹Universite de Montreal, Montreal, QC, Canada, ²Research Center, Hôpital du Sacré-Cœur de Montréal, Montreal, QC, Canada, ³Obstetric and Gynecology Department, CHU Ste-Justine, Montreal, QC, Canada.

4:00 PM–4:15 PM	Perception of Teratogenicity among Pregnant Women with Asthma or Diabetes Mellitus
	Sarangarm P¹, Liu S¹, Young BN¹, Phelan ST², Nawarskas J¹, Rayburn WF², Bakhireva LN¹. ¹University of New Mexico, College of Pharmacy, Albuquerque, NM, United States, ²University of New Mexico, Department of Obstetrics and Gynecology, Albuquerque, NM, United States.

4:45 PM–6:30 PM	50^th Anniversary Meeting Celebration—Marriott Ballroom VI
	Organized by the 50^th Anniversary Planning Committee

4:45 PM–4:50 PM	Introduction
	John M. Rogers, U.S. Environmental Protection Agency

4:50 PM–5:10 PM	Josef Warkany: Then and Now
	Wladimir Wertelecki, University of South Alabama

5:10 PM–5:30 PM	James G. Wilson, Embryologist, Teratologist, Founding Member of the Teratology Society, Superb Researcher, Teacher and Human Being
	Robert L. Brent, Alfred I. duPont Hospital for Children

5:30 PM–5:45 PM	Distinguished Service Award
	Presented by Barbara Hales and Terence Ozolins

5:45 PM–6:00 PM	Students' Viewpoints on the Future of the Teratology Society

6:00 PM–6:30 PM	Let’s Play Jeopardy! History of the Teratology Society