|
Tuesday, June 30, 2009 |
|
|
|
|
7:00 AM – 5:00 PM |
Registration |
|
|
|
|
6:30 AM – 7:00 AM |
Sunrise Mini Course Coffee and Breakfast |
|
|
|
|
7:00 AM – 8:30 AM
|
Sunrise Mini Course |
|
|
The Use of Single Nucleotide Polymorphism (SNP) Screening
in Diagnosis and Treatment
|
|
|
(Separate registration required) |
|
|
|
|
|
Organized by the Education Committee, Chairperson, Tacey E. White, GlaxoSmithKline |
|
|
|
|
7:00 AM – 7:45 AM |
The Identification of SNPs That Predispose to Birth Defects,
and Their Relation to Environmental Factors |
|
|
Speaker: A.
Steven Whitehead, University of Pennsylvania |
|
|
|
|
7:45 AM – 8:30 AM |
International
HapMap Project: The Use of SNP Screening to Identify Pharmacogenetic Determinants of Drug Response |
|
|
Speaker: Terreira
S. Jones, University of Tennessee, Memphis and St. Jude’s Hospital |
|
|
|
|
7:45 AM – 8:15 AM |
Coffee and Breakfast |
|
|
|
|
8:30 AM – 9:30 AM |
State-of-the-Art Lecture 2:
Environment and Child Health |
|
|
Chairperson: Elaine Faustman, University of Washington |
|
|
Speaker: Lizbeth
Lopez Carrillo, Nacional Institute of Public Health, Mexico
|
|
|
|
|
9:30 AM – 12:15 PM
|
Joint TS/NBTS/OTIS Symposium
|
|
|
Global Issues in Maternal and Child Health
|
|
|
Chairs: Gary Kimmel and Carole Kimmel, Private Consultants
|
|
|
|
|
9:30 AM – 9:35 AM |
Introduction |
|
|
|
|
9:35 AM – 10:10 AM |
HIV and Perinatal Transmission |
|
|
Speaker: Clemente
Diaz, University of Puerto Rico School of Medicine |
|
|
|
|
10:10 AM – 10:45 AM |
Environmental Disasters and Children's Health |
|
|
Speaker: Phil Landrigan, Mount Sinai School of
Medicine |
|
|
|
|
10:45 AM – 11:00 AM |
Break |
|
|
|
|
11:00 AM – 11:35 AM |
Maternal and Child Nutrition: Long Term Impacts on Disease in Low and Middle Income Countries |
|
|
Speaker: Linda S. Adair, The University of North
Carolina, Chapel Hill |
|
|
|
|
11:35 AM – 12:10 PM |
Treating Severe Malaria with Pre-Referral Artesunate Saves Lives and Prevents CNS Damage |
|
|
Speaker: Melba
Gomes, World Health Organization, Geneva Switzerland |
|
|
|
|
12:10 PM – 12:30 PM |
Conclusions |
|
|
|
|
12:30 PM – 1:30 PM
|
Lunch Box Session 2 |
|
|
Human Teratogens: The Year in Review |
|
|
Chairperson: Karen Filkins |
|
|
Speaker: Melissa Tassinari, Pfizer Inc. |
|
|
|
|
1:30 PM – 3:30 PM |
Platform Session 4
Congenital Heart Malformations: From Epidemiology to Mechanisms and Testing Techniques |
| |
Chairpersons: John M. Graham, Jr., Cedars-Sinai Medical Center and Helen Badham, Queen’s University |
| |
|
1:30 PM–1:45 PM |
Early-Pregnancy Opioid Analgesic Treatment and Risk for Congenital Heart Defects |
|
Broussard CS1, Rasmussen SA1, Reefhuis J1, Friedman JM2, Jann MW3, Honein MA1. 1Centers for Disease Control and Prevention, Atlanta, GA, United States, 2University of British Columbia, Vancouver, BC, Canada, 3Mercer University, Atlanta, GA, United States. |
| |
|
1:45 PM–2:00 PM |
Maternal Use of Bupropion and Risk for Congenital Heart Defects |
|
Alwan S1, Botto LD2, Correa A3, Rasmussen SA3, Reefhuis J3, Friedman JM1. 1Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada, 2Division of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City, UT, United States, 3National Center on Birth Defects and Development Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, United States. |
| |
|
2:00 PM–2:15 PM |
Risk of Malformations in Infants of Military and Employed Civilian Women |
|
Li T1, Cange CW1,2. 1University of Washington, Seattle, WA, United States, 2Ecole des Hautes Etudes en Sciences Sociales, Paris, France. |
| |
|
2:15 PM–2:30 PM |
Micro-Bubble Contrast High Frequency Ultrasound Imaging of the Chick Embryo Cardiovascular System |
|
Schellpfeffer MA, Kolesari GL. Medical College of Wisconsin, Milwaukee, WI, United States. |
| |
|
2:30 PM–2:45 PM |
Are Asthmatic Women More at Risk of Cardiac Malformations, Limb Malformations and Cleft Lip and/or Palate Than Non-Asthmatic Women? |
|
Blais L, Kettani F, Forget A. Université de Montréal, Montréal, QC, Canada. |
| |
|
2:45 PM–3:00 PM |
Role of HIF1 Pathways in Diabetic Embryopathy |
|
Pavlinkova G1, Kappen C2, Bohuslavova R1, Salbaum M2. 1Institute of Biotechnology, Prague, Czech Republic, 2Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, United States. |
| |
|
3:00 PM–3:15 PM |
Development of an In Vitro Technique to Use Mouse Embryonic Stem Cells (mESC) in Evaluating Effects of Xenobiotics |
|
Barrier M1, Jeffay S1, Nichols HP1, Slentz-Kesler K2, Hunter ES1. 1US Environmental Protection Agency, Research Triangle Park, NC, United States, 2Almac Diagnostics, Durham, NC, United States. |
| |
|
3:15 PM–3:30 PM |
Cardiovascular Defects in Mouse Embryos Lacking tgfbr2 in Cells Expressing SM22α |
| |
Washington IM, Sesti C, Jaffe M, Frutkin A, Chin MT, Dichek D. University of Washington, Seattle, WA, United States. |
|
|
|
3:30 PM – 3:45 PM |
Break |
|
|
|
|
3:45 PM – 5:45 PM |
ILSI/HESI Symposium |
|
|
Maternal Toxicity and Its Impact on Study Design and Data
Interpretation |
|
|
Chairpersons: James Kim, ILSI
Health and Environmental Sciences Institute and Bruce K. Beyer, sanofi-aventis
|
|
|
|
|
3:45 PM – 4:00 PM |
Overview and Background |
|
|
Speaker: Ronald D. Hood, Ronald D. Hood and Associates |
|
|
|
|
4:00 PM – 4:15 PM |
Exaggerated Pharmacology Versus True Toxicity, Part 1 |
|
|
Speaker: Bengt
Danielsson, PharmaNet Services GmbH |
|
|
|
|
4:15 PM – 4:30 PM |
Exaggerated Pharmacology Versus True Toxicity, Part 2 |
|
|
Speaker: Meredith S. Rocca, Amgen |
|
|
|
|
4:30 PM – 4:45 PM |
Relationships of Maternal and Fetal Weight Changes in Developmental
Toxicology Bioassays |
|
|
Speaker: Neil
Chernoff, U.S. Environmental Protection Agency |
|
|
|
|
4:45 PM – 5:00 PM |
Regulatory Perspectives and Case Studies |
|
|
Speaker: Wafa Harrouk, U.S. Food and Drug
Administration |
|
|
|
|
5:00 PM – 5:45 PM |
Round Table Discussion |
|
|
|
4:45 PM - 7:45 PM |
Joint TS/OTIS Pregnancy Registry Workshop Part 1 |
| |
Chairpersons: Christina D. Chambers, University of California, San Diego and Lewis B. Holmes, MassGeneral Hospital For Children |
| |
|
| 4:45 PM – 4:50 PM |
Introduction
Speaker: Lewis B. Holmes, MassGeneral Hospital for Children |
| |
|
| 4:50 PM – 5:05 PM |
Variability across Current Pregnancy Registry Designs: Impact on Interpretation of Results
Speaker: Laura McKain, Kendle International |
| |
|
| 5:05 PM – 5:25 PM |
Sources of Bias in Pregnancy Registries
Speaker: Gideon Koren, The Hospital For Sick Children |
| |
|
| 5:25 PM – 5:45 PM |
Retrospective Versus Prospective Registry Designs: A Place for Both
Speakers: Vince Armenti, National Transplant Registry and the Neoral Pregnancy Registry for Psoriasis and Rheumatoid Arthritis |
| |
|
| 5:45 PM – 6:00 PM |
Panel Discussion |
| |
|
| 6:00 PM - 7:45 PM |
Poster Session (Located in the Exhibit Hall) |
| |
|
|
5:45 PM – 7:45 PM |
TS/NBTS Joint Poster Session and Exhibits Open |
|
|
|
Information
(2.4 MB)