<<<Wednesday
Thursday, June 28, 2007

7:00 AM-10:30 AM REGISTRATION-17th Floor Alcove
   
7:30 AM–10:30 AM PLATFORM SESSION V—Grand Ballroom (17th Floor)
Genomics and Bioinformatics

Chairperson: Philip E. Mirkes, Texas A&M University and
Barbara D. Abbott, U.S. Environmental Protection Agency

8:00 AM-8:15 AM 46 A Genomic Approach to Hyperthermia-Induced Neural Tube Defects
    Barrier M, Mo Q, Vannucci M, Mirkes PE. Texas A&M University, College Station, TX, United States.
8:15 AM-8:30 AM 47 Metal-Induced Toxicogenomic Response in Resistant and Sensitive Mouse Strains Undergoing Neurulation
    Robinson JF, Yu X, Griffith WC, Hong S, Beyer RP, Faustman EM. University of Washington, Seattle, WA, United States.
8:30 AM-8:45 AM 48 The Genomic Response of Ishikawa Cells to Chemicals With Estrogenic Activity Supports Their Use as a Potential Alternative to Animal Testing for Estrogens
    Naciff JM, Khambatta ZS, Carr JG, Thomason RG, Reichling TD, Tiesman JP, Daston GP. The Procter and Gamble Company, Cincinnati, OH, United States.
8:45 AM-9:00 AM 49 Differential Programming of p53-Deficient Embryonic Cells During a Rotenone-Block Revealed by mRNA and MicroRNA Profiling
    Singh AV, Green ML, States JC, Knudsen TB. University of Louisville, Louisville, KY, United States.
9:00 AM-9:15 AM 50 Altered Developmental Programming of Fetal Liver by Prenatal Arsenic Exposure Associated With Accelerated Atherogenesis in ApoE-knockout Mice
    States JC1, Singh AV1, Miller HL1, Piao Y2, Ko MSH2, Srivastava S1, Knudsen TB1. 1University of Louisville, Louisville, KY, United States, 2National Institute on Aging, Baltimore, MD, United States.
9:15 AM-9:30 AM 51 Diabetic Embryopathy: Molecular Response of the Embryo and Role of the Placenta
    Kappen CT1,3, Pavlinkova G2, Kruger C1,2, Salbaum JM1,3. 1Pennington Biomedical Research Center/LSU, Barton Rouge, LA, United States, 2University of Nebraska Medical Center, Omaha, NE, United States, 3Munroe-Meyer Institute, Omaha, NE, United States.
9:30 AM-9:45 AM 52 Altered Developmental (Fetal) Programming of the Mouse Mammary Gland in Female Offspring Following Maternal Dietary Exposures
    Singh AV1, Luijten M2, de Vries A2, Piersma AH2, Knudsen TB1. 1University of Louisville, Louisville, KY, United States, 2RIVM, Bilthoven, Netherlands.
9:45 AM-10:00 AM 53 MicroRNA Expression Changes in Response to Hyperthermia During Early Postimplantation Mouse Development
    Barrier M1, Chen YA1, Shelton J2, Dugas DV2,3, Ford LP2, Mirkes PE1. 1Texas A&M University, College Station, TX, United States, 2Applied Biosystems, Austin, TX, United States, 3Rice University, Houson, TX, United States.
10:00 AM-10:15 AM 54 Chromatin, Human Stem Cells, and Tissue Engineering: Shifting Paradigms to Improve Relevancy in Developmental Toxicology Research
    Cho EL1, Li WJ2, Tuan RS2. 1Sciences International, Alexandria, VA, United States, 2NIH/NIAMS/CBOB, Bethesda, MD, United States.

 

   
7:30 AM–10:30 AM PERSONALIZED NUTRITION AND MEDICINE: IMPACT ON PERINATAL DEVELOPMENT SYMPOSIUM-Urban (17th Floor)

Chairpersons: William Slikker, Jr., National Center for Toxicological Research, U.S. Food and Drug Administration and
Charlotte Anne Hobbs, University of Arkansas for Medical Sciences

 

7:30 AM-8:10 AM S22 The Importance of Personalized Medicine and Nutrition: What it is and Why it is Critical; Barriers and Bridges
    Speaker: Melissa S. Tassinari, Pfizer Inc.
8:10 AM-8:50 AM S23 Molecular Epidemiological Tool Kit for Personalized Medicine
    Speaker: Charlotte Anne Hobbs, University of Arkansas for Medical Sciences
8:50 AM-9:30 AM S24 Examples of Associations Between Polymorphisms and Birth Defects: Folic Acid and Retinoic Acid
    Speaker: Deborah K. Hansen, National Center for Toxicological Research, U.S. Food and Drug Administration
9:30 AM-10:10 AM S25 Susceptibility to the Developmental Neurotoxicity of Anesthetics: Studies on Neuroprotection
    Speaker: William Slikker, Jr., National Center for Toxicological Research, U.S. Food and Drug Administration
   
10:30 AM–12:30 PM ACHIEVING WORLDWIDE ELIMINATION OF FOLIC ACID-PREVENTABLE SPINA BIFIDA AND ANENCEPHALY WORKSHOP -Urban (17th Floor)

Chairperson: Robert L. Brent, AI DuPont Hospital for Children and Thomas Jefferson University

10:30 AM-10:50 AM W5 Introduction to Achieving Worldwide Elimination of Folic Acid-Preventable Spina Bifida and Anencephaly
    Speaker: Robert L. Brent, AI DuPont Hospital for Children and Thomas Jefferson University
10:50 AM-11:10 AM W6 Progress Towards Worldwide Prevention of Folic Acid Preventable Spina Bifida
    Speaker: Godfrey P. Oakley, Rollins School of Public Health, Emory University
11:10 AM-11:30 AM W7 New and Continuing Policy Issues About Optimal Fortification of Flour with Folic Acid and VitaminB12
    Speaker: Gilbert S. Omenn, University of Michigan Medical School
11:30 AM-11:50 AM W8 Review of Evidence Base for Tolerable Upper Level of Folic Acid
    Speaker: Robert J. Berry, National Center on Birth Defects and Developmental Disabilities, CDC
11:50 AM-12:10 PM W9 Will Increasing the Level of Folic Acid Fortification of Enriched Flours Further Reduce Neural Tube Defects (NTDs) Without Causing Harm?
    Speaker: Richard B. Johnston, Jr., University of Colorado, School of Medicine
12:10 PM-12:30 PM   Discussion

 

   
10:30 AM–1:00 PM REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF THERAPEUTIC ESTROGEN RECEPTOR MODULATORS-Grand Ballroom (17th Floor)

Chairpersons: Donald G. Stump, WIL Research Laboratories, LLC and
Judith W. Henck, Eli Lilly & Company

Sponsored by Midwest Teratology Association

10:30 AM-10:40 AM   Introduction
    Speaker: Donald G. Stump
10:40 AM-11:20 AM W10 Estrogen Receptor Biology and Current Research Directions
    Speaker: Kenneth S. Korach, National Institute of Environmental Health Sciences
11:20 AM-12:00 PM W11 Reproductive and Developmental Toxicity of Therapeutic Estrogen Receptor Modulators
    Speaker: Judith W. Henck, Eli Lilly & Company
12:00 PM-12:40 PM W12 Reproductive and Developmental Toxicity of Phytoestrogens
    Speaker: K. Barry Delclos, National Center for Toxicological Research, U.S. Food and Drug Administration
12:40 PM-1:00 PM   What Does the Future Hold for Estrogen Receptor Modulators?
    Panel Discussion/Audience

 

   
1:00 PM–4:00 PM

COUNCIL II MEETING-Allegheny (17th Floor)

 

rev. 6-April, 2007

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