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2002 Meeting Highlights

Scottsdale, Arizona
June 22 - 27, 2002

Registration Information

Program

PDF of Final Program

Neurobehavioral Teratology Society
Preliminary Schedule

Call for Abstracts and
Instructions for Student/Young
Investigators Awards

Continuing Education Course

Presentation / Poster Instructions

Exhibitors

Sustaining Members and Meeting Sponsors

Sponsor Opportunities

Registration Information



Program

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Quick Index (click the day at top to go there) 

Saturday, June 22 Sunday,
June 23
Monday,
June 24
Tuesday,
June 25
Wednesday,
June 26
Thursday,
June 27
           
Education Course Education Course continued

WARKANY LECTURE
Kenneth Lyons Jones

Mini course: Experimental design and biostatistics Concurrent Sessions SYMPOSIUM - Immunotoxicology: Principles and Applications to Developmental Toxicity Studies
  SYMPOSIUM - Application of Proteomics to Developmental Toxicology Wilson Publication Award Presentation and Address SYMPOSIUM - Prediction of Risk from Animal Models and Clinical Studies "PREVENTING BIRTH DEFECTS THROUGH PUBLIC POLICY" James G. Wilson and Clarke Fraser Awards Luncheon
    Student Plenary Session and Platform Award Competition "TERATOLOGY: BIG PICTURE PERSPECTIVE" Concurrent Platform sessions  
    The Great Debate: Is there an all or none phenomenon in Teratology? TERATOGEN UPDATE, (TS/ OTIS Joint Session) Banquet  
    SYMPOSIUM - Methylmercury: From Minamata Bay to Current Policy Implementation Joint Teratology/NBTS Poster Session II    
    Joint TS/NBTS/
OTIS Poster Session I
     
    Student Career Event      

 

 

 

 

Saturday, June 22
   
1:15 PM - 4:30 PM EDUCATION COURSE

Mechanisms, Biomarkers, Data Interpretation: An Integrative Risk Assessment Using Developmental Neurotoxicity as a Model
  • Use of mechanistic data in risk assessment
Carole Kimmel, USEPA
  • General overview of pre & postnatal nervous system development
John DeSesso, Mitretek Systems
  • Molecular markers of nervous system development and toxicity
James P. O,Callaghan, CDC/NIOSH
  • Functional markers of nervous system development and manifestations of toxicity
Patricia Rodier, University of Rochester

 

Sunday, June 23

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8:15 AM - 11:30 AM EDUCATION COURSE (CONTINUED FROM SATURDAY)
  • Developmental neurotoxicity: Testing and data interpretation (focus on practical and logistical considerations, data interpretation and challenges)
Abby A. Li, Monsanto Company
  • Examination of the effects of chlorpyrifos on developmental processes: evaluation of biochemical, morphological and behavioral indices of developmental neurotoxicity
Stan Barone, USEPA
  • Integrative risk assessment: BBDR modeling
Elaine Faustman, University of Washington
  • Panel discussion. Beginning with set of predetermined questions related to applications of mechanistic information in applied research, testing and risk assessment
Facilitator: Joseph Holson, WIL Research Laboratories, Inc.
1:00 PM - 4:30 PM MARCH OF DIMES SYMPOSIUM

The Application of Proteomics to Developmental Toxicology
  • Introduction
Patrick Wier, GlaxoSmithKline
  • Mining proteomic diversity with LC-MS and the SALSA algorithm
Daniel C. Liebler, University of Arizona
  • Direct profiling of proteins in biological tissue sections by MALDI mass spectrometry
David L. Hachey, Vanderbilt University
  • Qualitative and quantitative proteomics without polyacrylamide
David Goodlett, The Institute for Systems Biology, University of Washington
  • Spot the difference: The effects of hypoxia on the cytotrophoblast protein repertoire
Van Hoang, National Cancer Institute
  • Student Discussions with MOD Symposium Speakers
5:00 PM - 6:00 PM ISSUES FORUM
 5:00 PM - 7:30 PM EXHIBITS OPEN
6:00 PM - 7:30 PM WELCOMING RECEPTION

 

Monday, June 24

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8:00 AM 9:00 AM WARKANY LECTURE
From recognition to responsibility: David Smith, Josef Warkany and the fetal alcohol syndrome in the 21 st century.

Speaker: Kenneth Lyons Jones
9:00 AM - 10:00 AM Wilson Publication Award Presentation and Address
10:00 AM - 12:00 PM

Student Plenary Session and Platform Award Competition

Chairpersons: Janet Urui-Adams, University of California, Davis, and Jack Bishop, NIEHS

12:15 PM - 1:00 PM

The Great Debate: Is there an all or none phenomenon in Teratology?
Moderator: Mason Barr, University of Michigan

Presenters: Robert Brent, DuPont Hospital for Children and Joe Rutledge, University of Washington

1:30 PM 4:45 PM PUBLIC AFFAIRS SYMPOSIUM

Methylmercury: From Minamata Bay to Current Policy Implementation
  • Historical Methylmercury Exposure and Developmental Toxicity
Kenneth Reuhl, Rutgers University
  • Recent Studies on the Health Effects of Methylmercury
David Bellinger, Harvard University
  • EPA Hazard Assessment for Methylmercury Relies on Recent Epidemiological Studies
Deborah Rice, USEPA
  • Management and Communication of Risk: The Maine Experience
Andrew E. Smith, Maine
5:00 PM - 7:30 PM Joint TS/NBTS/OTIS Poster Session I
7:30 PM - 10:30 PM Student Career Event

 

Tuesday, June 25

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7:00 AM - 8:15 AM Mini course: Experimental design and biostatistics
  • Basic Statistical Analysis of Developmental Toxicity Studies
Instructor: Woody Setzer, USEPA
  • Evaluation of Post-natal Developmental Outcomes: Study Design Considerations for Endocrine Active Chemicals.
Instructor: Paul Foster, CIIT Centers for Health Research
8:30 AM -11:45 AM NBTS/OTIS/Teratology Society/European Teratology Society Joint Symposium

Children's Health and Environmental Chemical Exposures: Prediction of Risk from Animal Models and Clinical Studies
  • The role of the environment in the neurodevelopmental modulation in children exposed in utero to illicit drugs or maternal diseases
Asher Ornoy, Hebrew University
  • Developmental outcome of children exposed in utero to antiepileptic drugs
Lew Holmes, Massachusetts General Hospital and Jane Adams, University of Massachusetts
  • Use of identical behavioral tasks in children and nonhuman primates for studying chemical effects on a variety of complex brain functions
Merle Paule, NCTR
  • Use of imaging techniques to explore neural substrates associated with prenatal alcohol syndrome
Elizabeth R. Sowell, UCLA
12:00 - 12:45 PM "TERATOLOGY: BIG PICTURE PERSPECTIVE"
Bernard Schwetz, Acting Principal Deputy Commissioner FDA
1:00 PM - 4:00 PM TERATOGEN UPDATE, (TS/OTIS Joint Session)
  • Caffeine - a human teratogen?
Mildred Christian, Argus Research, a division of Charles River Laboratories
  • Cholesterol lowering drugs (the statins)
Robert Brent, DuPont Hospital for Children
  • Vitamin A
Andrew Hendrickx, California Regional Primate Research Center
  • Binge drinking
Janine Polifka, University of Washington
5:00 PM - 7:30 PM Joint Teratology/NBTS Poster Session II

 

Wednesday, June 26

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Concurrent Sessions

8:30 AM - 11:30 AM THE USE OF NONHUMAN PRIMATE MODELS IN DEVELOPMENTAL TOXICOLOGY STUDIES
  • The Non-Human Primate Model in Reproductive Toxicology with Special Emphasis on Male Fertility Testing
Walter H. Bee, Charles River Laboratories
  • Chronic Uterine and Vascular Female Catheterization Techniques and Opportunities for Investigative Studies
George J. Haluska, Oregon Regional Primate Research Center
  • Female Reproduction and Prenatal Development of the Immune System in Macaques
Andrew G. Hendrickx, California Regional Primate Research Center
  • Preclinical Development Strategy for Testing Effects of Immune Modulating HuMAb in Reproduction in Non-human Primates
Corine K. Klingbeil, Protein Design Labs, Inc.
  • Neurobehavioral Testing in the Rhesus Monkey
Nellie K. Laughlin, University of Wisconsin
8:30 AM - 11:30 AM THE DIRECT DOSING OF PRE-WEANING MAMMALS IN TOXICITY TESTING
  • General experimental design issues in direct dosing of pre-weaning mammals
Sue Makris, USEPA
  • Direct dosing of pre-weaning rodents
Susan Barron, University of Kentucky
  • Direct dosing of pre-weaning pigs, dogs and primates
Larry Garthoff, CFSAN/FDA
  • Direct dosing of Pre-Weaning Mammals. Panel Discussion
Chaired by Isabel Walls, ILSI
Panelists: Sue Makris, Susan Barron, Larry Garthoff, David Beckman, Tom Sobotka, CFSAN/FDA
8:30 AM - 11:30 AM MICROARRAY DATA ANALYSIS AND BIOINFORMATICS WORKSHOP (Sponsored by Perkin-Elmer Life Sciences)
  • Standards and practices of microarray analysis in developmental biology and developmental toxicity
Tom Knudsen, Jefferson Medical College and George P. Daston, Procter & Gamble Company, Miami Valley Laboratories
  • Toxicogenomics: use of a data set of toxicant-induced transcriptional profiles to derive signature patterns associated with mode of action
Mark Johnson, Robert Wood Johnson Pharmaceutical Research Institute
  • Bioinformatics pipeline and its information resources
Sylvia J. Spengler, Lawrence Berkeley National Laboratory
  • Morphant-based gene knockdown
Stephen C. Ekker, University of Minnesota
12:00 - 12:45 PM "PREVENTING BIRTH DEFECTS THROUGH PUBLIC POLICY"
Jose Cordero, Director National Center on Birth Defects and Developmental Disabilities, CDC
1:00 PM - 5:00 PM

PLATFORM SESSIONS (3 Concurrent Sessions) Selected from submitted abstracts

Clinical Teratology and Epidemiology

Abnormal Development

Hazard and Risk Evaluation

5:00 PM - 6:00 PM BUSINESS MEETING
7:00 PM - 8:00 PM BANQUET RECEPTION
8:00 PM BANQUET

 

Thursday, June 27

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8:30 AM - 11:30 AM The Wiley-Liss Symposium

Immunotoxicology: Principles and Applications to Developmental Toxicity Studies
  • The Postnatal Immune System as a Target for Teratogens/ Developmental Toxicants from Perinatal Exposures
Michael Luster, CDC, NIOSH
  • In Utero and Postnatal Development of the Immune System
Ralph J. Smialowicz, USEPA, NHEERL
  • Windows of Differential Immunotoxic Sensitivities during Development: Phylogenetic and Sub-population Considerations
Rodney R. Dietert, Cornell Univ.
  • The Effect of the Maternal Immune System on Teratogenicity
Steven D. Holladay, VA-MD Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University
11:45 AM - 1:00 PM James G. Wilson and Clarke Fraser Awards Luncheon

 

 



Instructions for Presentations and Posters

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Oral Presentations
Each platform paper, except for those presented in the symposia, will be allowed 15 minutes (12 minutes for presentations and 3 minutes for discussion). The time schedule will be strictly followed. Projectors for 35 mm slides will be available in each meeting room. Please keep slides simple and uncluttered.

A good rule of thumb is, if you cannot read your slide without magnification, those in the middle and rear of the room will be unable to read it when presented. One concept per slide and a maximum rate of one slide per minute, are also good rules to follow for effective presentations.

Poster Presentations
Poster material should be organized within a 4 ft. x 8 ft. area. The top of your poster board should contain the following information, with letters at least 3/4 inches high:

  1. Your poster number
  2. Title
  3. Authors
  4. Affiliations

A copy of the abstract should be posted towards the upper-left corner, and a set of conclusions toward the lower- right corner of your poster. These should be printed in letters about 1/4 inch high. Poster information should be legible from a distance of at least 3 to 4 feet. Material, including line drawings, should be clearly presented and may be computer generated (laser printer is preferable). PLEASE BRING YOUR OWN PUSH-PINS. Poster sessions and times for setup and removal are indicated in the Program.

Posters should be on display from 11:00 AM - 10:00 PM on Monday, June 26, or 11:00 AM - 10:00 PM on Tuesday, June 27. Those presenting should plan to be present on Monday or Tuesday evenings from 7:30 PM - 10:00 PM. All posters should be removed immediately following the poster session at which you presented (10:00 PM).



EXHIBITORS

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The Teratology Society thanks the following organizations for their participation as exhibitors at the 2002 Annual Meeting.

Clinical Trials BioResearch, Ltd. ISIS BioComp
Elsevier Science, Inc. John Wiley & Sons, Inc.
EMBI TEC San Diego Instruments, Inc.
Hamilton-Kinder Sierra Biomedical, Inc.
Hamilton Thorne Research SNBL USA, Ltd.
Huntingdon Life Sciences TherImmune Research Corporation
IIT Research Institute Toxicology Research Laboratory
Instem Life Sciences, Ltd.

 


2002 Sustaining Members

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The Teratology Society thanks the following organizations
for their generous support of the Teratology Society.

 


To Be Announced

 


2002 Meeting Sponsors

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The Teratology Society thanks the following Sponsors
for their support of the 2002 meeting

AstraZeneca
Aventis Pharmaceuticals
The Dow Chemical Company
Eli Lilly and Company
GlaxoSmithKline Pharmaceuticals
John Wiley & Sons
March of Dimes
Middle Atlantic Reproduction & Teratology Association
Monsanto Company
Midwest Teratology Association
National Center on Birth Defects Developmental Disabilities, CDC
National Institute of Child and Human Development
National Institute of Environmental Health Sciences
PerkinElmer Life Sciences
Society of Toxicology
Wetzel Contributors
WIL Research Laboratories
Wyeth-Ayerst Pharmaceuticals

 

rev. 10-Jun-2003

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